Deisovalerylblastmycin produced by Streptomyces SP.

نویسندگان

  • T Ishiyama
  • T Endo
  • N Otake
  • H Yonehara
چکیده

A new antifungal antibiotic was isolated from the fermentation broth of Streptomyces sp. 5140-A1. Degradation studies of the crystalline antibiotic, m.p. 186 approximately 188 degrees C, C21H28O8N2, suggested Piricularia oryzae and less toxicity against killfish than antimycin A--blastmycin antibiotics.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Kitamycins, new antimycin antibiotics produced by Streptomyces sp.

In the course of our screening program for plant growth inhibitors, Streptomyces sp. K385 isolated from a soil sample collected in OkayamaJapan, was found to produce kitamycin A (1) and B (2), new antimycin type antibiotics, together with known antimycin type antibiotics, antimycin A1? A2a, A3, A4a1?2), urauchimycin B (3)3), and deisovalerylblastmycin (4).4?5) This study describes the fermentat...

متن کامل

Cytotoxicity effect of secondary metabolites of Streptomyces koyangensis and Streptomyces tunisiensis isolated from saline soils of Garmsar City on human breast cancer cell line (MCF-7, IBRC C10082)

Background: Streptomyces is one of the most important prokaryotic microorganisms, and their secondary metabolites have high antimicrobial and cytotoxic properties. Three-quarters of the antibiotics known to be produced by these bacteria. As a result, finding new effective compounds from these microorganisms can be a way to treat cancer. The aim of this study was to isolate and screen halophilic...

متن کامل

Antioxidant and cytotoxic activities of metabolites produced by a new marine Streptomyces sp. isolated from the sea cucumber Holothuria leucospilota

Marine microorganisms are important sources for novel natural products. Hence, the aim of this study was to introduce marine microorganisms with the capability of producing antioxidant and cytotoxic metabolites. For this purpose, ten live sea cucumbers (Holothuria leucospilota) were collected from Larak Island, Persian Gulf. Then, their intestine contents were serially diluted and treated by he...

متن کامل

Extraction and Identification of Antibacterial Secondary Metabolites From Marine Streptomyces sp. VITBRK2

Actinomycetes were isolated from marine sediment samples collected from the east coast of Chennai, Tamil Nadu, India. Well diffusion and agar plug methods were used for the evaluation of antibiotic production by these isolates against drug resistant Methicillin- resistant Staphylococcus aureus (MRSA) and vancomycin resistant Enterococci (VRE). The potential isolate VITBRK2 was mass cultured for...

متن کامل

Optimization of Culture Conditions for Keratinase Production in Streptomyces Sp. JRS19 for Chick Feather Wastes Degradation

The aim of this study was to find the optimal conditions of a newly isolated Streptomyces strain JRS 19. Screening for keratinase producing bacteria and their keratinase production were investigated. The keratinase produced by the isolate was purified by chromatographic techniques and the optimum pH maintained was 7.0 and maintained at different temperatures Viz., 20ºC, 25ºC, 30ºC, 35ºC and 40º...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • The Journal of antibiotics

دوره 29 8  شماره 

صفحات  -

تاریخ انتشار 1976